Cortes E, Lachowski D, Robinson B, Sarper M, Teppo J, Thorpe S, Lieberthal T, Iwamoto K, Lee D, Okada‐Hatakeyama M, Varjosalo M, del Río Hernández A. Tamoxifen mechanically reprograms the tumor microenvironment via HIF‐1A and reduces cancer cell survival. EMBO Reports 2019.
Cortes E, Sarper M, Robinson B, Lachowski D, Chronopoulos A, Thorpe S, Lee D, del Río Hernández A. GPER is a mechanoregulator of pancreatic stellate cells and the tumor microenvironment. EMBO Reports 2019.
Dooling and Discher DE Inhibiting tumor fibrosis and actomyosin through GPCR activation. Trends in Cancer 2019.
The cover of the January 2019 issue highlights our back to back EMBO reports manuscripts (above). Click here
Pein and Oskarsson. Tamoxifen calms down the distressed PDAC stroma. News and Views about our back to back EMBO reports manuscripts. Read it here
Lachowski D, Cortes E, Rice A, Pinato D, Rombouts K, and del Río Hernández A. Matrix stiffness modulates the activity of MMP-9 and TIMP-1 in hepatic stellate cells to perpetuate fibrosis. Scientific Reports 2019
Matellan C, del Rio Hernandez A. Engineering the cellular mechanical microenvironment – from bulk mechanics to the nanoscale. Journal of Cell Science 2019
Matellan C, del Rio Hernandez A. Where No Hand Has Gone Before: Probing Mechanobiology at the Cellular Level. ACS Biomaterials Science and Engineering 2019
Rice A, del Rio Hernandez A. The Mutational Landscape of Pancreatic and Liver Cancers, as Represented by Circulating Tumor DNA. Frontiers in Oncology 2019
Kwong Hong Tsang D, Lieberthal T, Watts C, Dunlop IE, Ranadan S, del Rio Hernandez A, and Klein N. Chemically Functionalised Graphene FET Biosensor for the Label-free Sensing of Exosomes. Scientific Reports 2019.
Perone Y, Farrugia AJ, Meira AR, Győrffy B, Ion C, Uggetti A, Chronopoulos A, Marrazzo P, Faronato M, Shousha S, Davies C, Steel JH, Patel N, Del Rio Hernandez A, Coombes C, Pruneri G, Lim A, Calvo F, Magnani L. SREBP1 drives Keratin-80-dependent cytoskeletal changes and invasive behavior in endocrine-resistant ERα breast cancer. Nature Communications 2019