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CMBL identifies a new mechanotransduction pathway that involves a tumor suppressor protein and talin. This mechanism regulates cellular processes downstream RhoA.

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To read the article:
https://doi.org/10.1371/journal.pbio.2005599

"Mechanotransduction in talin through the interaction of the R8 domain with DLC1." PLoS Biology (2018).

Alexander William M. Haining, Rolle Rahikainen, Ernesto Cortes, Dariusz Lachowski, Alistair Rice, Magdalena von Essen, Vesa P. Hytönen, Armando del Río Hernández