ARTICLE: RAR-B is downregulated in HCC & cirrhosis and its expression inhibits myosin-driven activation and durotaxis in hepatic stellate cells
Our latest article, where we show how retinoic acid receptor beta (RAR-beta) is downregulated in liver cancer (HCC, hepatocellular carcinoma). We also show that expression and activation of RAR-beta inhibits cell mechanics, downregulating myosin expression and inhibiting the process of durotaxis.